Here is a neat little trick you can use to target Safari and make it behave while fixing cross browser layouts. This method will allow you to keep a page valid and it will allow you to only target Safari.
Now, like I stated above this will target all browsers that currently support webkit and add support for it in the future so you cannot rely on only this. So now you need to create the css file and add some code that is Safari specific by using the double # method. Some people will ask, why not just include the double # to begin with? And the simple answer is that it will cause your CSS not to validate.
Here is the example css code that will target only Safari
add this code to the top of the master page or template you wish to include ads on:
Now add this code to the area of the page you want your ads to be displayed: